Toradol (ketorolac) is a potent non-steroidal anti-inflammatory drug (NSAID) that is typically administered orally or through an intramuscular injection. However, it is increasingly used as an intra-articular injection, meaning it is delivered directly into a joint to provide localized pain relief without the specific risks associated with corticosteroids.
While steroid injections are the traditional choice for joint inflammation, Toradol offers a different mechanism of action that may be preferable for certain patients.
Non-Steroidal Action: Because it is an NSAID, it does not carry the risks of skin thinning, fat atrophy, or tendon weakening associated with steroids.
Diabetes Friendly: Unlike corticosteroids, Toradol does not cause a spike in blood sugar levels, making it a safer alternative for patients with poorly controlled diabetes.
Rapid Onset: It works quickly to inhibit prostaglandins, the chemicals in the body that signal pain and cause inflammation.
Short-Term Bridge: It is often used for patients who have already reached their yearly limit of steroid injections but still require localized relief.
While Toradol is effective, there are specific precautions to keep in mind regarding its use in a joint.
Bleeding Risk: As an NSAID, Toradol can thin the blood slightly. Patients on blood thinners or those with bleeding disorders should consult their doctor.
Kidney Function: NSAIDs are processed through the kidneys. Even though a joint injection is localized, patients with significant kidney disease may need to avoid this treatment.
Allergies: Patients with a history of aspirin-sensitive asthma or severe NSAID allergies should not receive Toradol.
Shorter Duration: The primary drawback compared to a steroid or a sustained-release drug like Zilretta is that the pain relief from Toradol typically does not last as long.